Document Detail


X-linked megalocornea. Ocular findings and linkage analysis.
MedLine Citation:
PMID:  1754164     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A family with X-linked megalocornea (XMC) is presented. The most typical ocular features of the disease (cornea globosa, arcus lipoides, mosaic dystrophy of the cornea, pigment dispersion, and cataract) are described and their diagnostic value is discussed by reviewing the literature. Linkage data suggest that the XMC locus maps in the region Xq13-q25, most probably in Xq21-q22.
Authors:
F M Meire; E M Bleeker-Wagemakers; M Oehler; A Gal; J W Delleman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Ophthalmic paediatrics and genetics     Volume:  12     ISSN:  0167-6784     ISO Abbreviation:  Ophthalmic Paediatr Genet     Publication Date:  1991 Sep 
Date Detail:
Created Date:  1992-01-28     Completed Date:  1992-01-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8206832     Medline TA:  Ophthalmic Paediatr Genet     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  153-7     Citation Subset:  IM    
Affiliation:
University Clinic, Department of Ophthalmology, Ghent, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Adult
Child
Corneal Dystrophies, Hereditary / diagnosis,  genetics*
Female
Humans
Linkage (Genetics) / genetics*
Male
Pedigree
X Chromosome*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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