| Wound healing studies of Aristolochia bracteolata Lam. with supportive action of antioxidant enzymes. | |
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MedLine Citation:
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PMID: 13678243 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Aristolochia bracteolata is a perennial herb, the leaves of which are used by the native tribals and villagers of the Chittoor District of Andhra Pradesh in India for the rapid healing of cuts and wounds. The ethanol extract of the shade-dried leaves of Aristolochia bracteolata Lam. was studied for its effect on wound healing in rats, using incision, excision and dead-space wound models, at two different dose levels of 400 and 800 mg/kg/body wt./day. The plant showed a definite, positive effect on wound healing, with a significant increase of the level of two powerful antioxidant enzymes, super oxide dismutase and catalase, in the granuloma tissue. |
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Authors:
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A Shirwaikar; A P Somashekar; A L Udupa; S L Udupa; S Somashekar |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Phytomedicine : international journal of phytotherapy and phytopharmacology Volume: 10 ISSN: 0944-7113 ISO Abbreviation: Phytomedicine Publication Date: 2003 |
Date Detail:
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Created Date: 2003-09-18 Completed Date: 2004-01-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9438794 Medline TA: Phytomedicine Country: Germany |
Other Details:
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Languages: eng Pagination: 558-62 Citation Subset: IM |
Affiliation:
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Department of Pharmacognosy, College of Pharmaceutical Sciences, Manipal, India. annie.shirwaikar@cops.manipal.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antioxidants / metabolism* Aristolochia* Catalase / biosynthesis Female India Male Medicine, Traditional Phytotherapy* Plant Extracts / administration & dosage, pharmacology*, therapeutic use Plant Leaves Rats Skin / drug effects*, enzymology, injuries*, pathology Superoxide Dismutase / biosynthesis Wound Healing / drug effects* |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Plant Extracts; EC 1.11.1.6/Catalase; EC 1.15.1.1/Superoxide Dismutase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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