| Wound healing activity of root extracts of Berberis lyceum royle in rats. | |
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MedLine Citation:
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PMID: 17295382 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The wound healing activities of the aqueous and methanol extracts of the root of Berberis lyceum were assessed using incision, excision and dead wound space models of wound repair in rats. After application of both extracts it was observed that the area of epithelialization increased, followed by an increase in wound contraction, skin breaking strength, tissue granulation, dry weight and hydroxyproline content. Histopathological studies of the granulation tissue also indicated that there was an increase in collagen formation in those rats treated with the methanol extract, compared with the control group animals. The methanol extract was more effective than the aqueous extract, but both showed significant results compared with the control. |
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Authors:
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A Asif; G Kakub; S Mehmood; R Khunum; M Gulfraz |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Phytotherapy research : PTR Volume: 21 ISSN: 0951-418X ISO Abbreviation: Phytother Res Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-05-22 Completed Date: 2007-09-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8904486 Medline TA: Phytother Res Country: England |
Other Details:
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Languages: eng Pagination: 589-91 Citation Subset: IM |
Copyright Information:
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(c) 2007 John Wiley & Sons, Ltd. |
Affiliation:
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Department of Biochemistry, University of Arid Agriculture, Murree Road, Rawalpindi, Pakistan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Berberis / chemistry* Epithelium / drug effects, pathology, physiopathology Female Male Methanol / chemistry Plant Extracts / chemistry, pharmacology* Plant Roots / chemistry* Rats Water / chemistry Wound Healing / drug effects* |
| Chemical | |
Reg. No./Substance:
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0/Plant Extracts; 67-56-1/Methanol; 7732-18-5/Water |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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