Document Detail

Wound complications from surgery in pregnancy-associated breast cancer (PABC).
MedLine Citation:
PMID:  20519803     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: there are concerns that physiologic changes of the peripartum breast may result in complications in breast conservation therapy. We present the complications of breast conservation surgeries and mastectomies performed for pregnancy-associated breast cancer (PABC).
MATERIALS AND METHODS: from April 1989 through April 2008, sixty-seven breast cancer patients underwent surgical management for PABC, defined as surgery during pregnancy or within one year postpartum. Records of women who had surgery were examined for post-operative wound complications of milk fistula, cellulitis, abscess, or hematoma.
RESULTS: Forty-seven patients underwent mastectomy. Twenty were treated with conservative breast surgery. There were six complications, all treated in the outpatient setting. There were no documented milk fistulae.
CONCLUSIONS: in our series, we had few postoperative complications and no milk fistulae for those patients undergoing surgery for PABC. When compared to those who had mastectomy for PABC, women who underwent breast conserving therapy did not appear to have increased frequency of surgical complications.
Laura S Dominici; Henry M Kuerer; Gildy Babiera; Karin M E Hahn; George Perkins; Lavinia Middleton; Mildred M Ramirez; Wei Yang; Gabriel N Hortobagyi; Richard L Theriault; Jennifer K Litton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Breast disease     Volume:  31     ISSN:  1558-1551     ISO Abbreviation:  Breast Dis     Publication Date:  2010  
Date Detail:
Created Date:  2011-01-20     Completed Date:  2011-06-01     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  8801277     Medline TA:  Breast Dis     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  IM    
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MeSH Terms
Abscess / etiology
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Breast Diseases / etiology*
Breast Neoplasms / diagnosis,  pathology,  surgery*
Cellulitis / etiology
Combined Modality Therapy
Cyclophosphamide / administration & dosage
Doxorubicin / administration & dosage
Fluorouracil / administration & dosage
Hematoma / etiology
Mastectomy, Modified Radical / adverse effects*
Mastectomy, Segmental / adverse effects*
Postpartum Period
Pregnancy Complications, Neoplastic / diagnosis,  pathology,  surgery*
Retrospective Studies
Young Adult
Reg. No./Substance:
80168379AG/Doxorubicin; 8N3DW7272P/Cyclophosphamide; U3P01618RT/Fluorouracil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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