Document Detail


Worsening bradycardia following antithymocyte globulin treatment of severe aplastic anemia.
MedLine Citation:
PMID:  22479166     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Immunosuppressive regimens, which include antithymocyte globulin (ATG), are widely used for the treatment of severe aplastic anemia (SAA). However, bradycardia has been reported only as a rare side effect of ATG therapy in the manufacturer's product information and, in rare cases, in the adult literature. We present an adolescent with SAA and preexisting bradycardia who underwent immunosuppression therapy with ATG, methylprednisolone, and tacrolimus and developed profound sinus bradycardia with successive doses of ATG.
Authors:
Justin Godown; Allison M Deal; Kathy Riley; Frederique Bailliard; Julie Blatt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG     Volume:  16     ISSN:  1551-6776     ISO Abbreviation:  J Pediatr Pharmacol Ther     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2012-04-05     Completed Date:  2012-08-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101089851     Medline TA:  J Pediatr Pharmacol Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  218-21     Citation Subset:  -    
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