| Worsening bradycardia following antithymocyte globulin treatment of severe aplastic anemia. | |
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MedLine Citation:
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PMID: 22479166 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Immunosuppressive regimens, which include antithymocyte globulin (ATG), are widely used for the treatment of severe aplastic anemia (SAA). However, bradycardia has been reported only as a rare side effect of ATG therapy in the manufacturer's product information and, in rare cases, in the adult literature. We present an adolescent with SAA and preexisting bradycardia who underwent immunosuppression therapy with ATG, methylprednisolone, and tacrolimus and developed profound sinus bradycardia with successive doses of ATG. |
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Authors:
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Justin Godown; Allison M Deal; Kathy Riley; Frederique Bailliard; Julie Blatt |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG Volume: 16 ISSN: 1551-6776 ISO Abbreviation: J Pediatr Pharmacol Ther Publication Date: 2011 Jul |
Date Detail:
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Created Date: 2012-04-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101089851 Medline TA: J Pediatr Pharmacol Ther Country: United States |
Other Details:
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Languages: eng Pagination: 218-21 Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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