| World Health Organization Pulmonary Hypertension group 2: pulmonary hypertension due to left heart disease in the adult--a summary statement from the Pulmonary Hypertension Council of the International Society for Heart and Lung Transplantation. | |
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MedLine Citation:
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PMID: 22884380 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Pulmonary hypertension associated with left heart disease is the most common form of pulmonary hypertension encountered in clinical practice today. Although frequently a target of therapy, its pathophysiology remains poorly understood and its treatment remains undefined. Pulmonary hypertension in the context of left heart disease is a marker of worse prognosis and disease severity, but whether its primary treatment is beneficial or harmful is unknown. An important step to the future study of this important clinical problem will be to standardize definitions across disciplines to facilitate an evidence base that is interpretable and applicable to clinical practice. In this current statement, we provide an extensive review and interpretation of the current available literature to guide current practice and future investigation. At the request of the Pulmonary Hypertension (PH) Council of the International Society for Heart and Lung Transplantation (ISHLT), a writing group was assembled and tasked to put forth this document as described above. The review process was facilitated through the peer review process of the Journal of Heart and Lung Transplantation and ultimately endorsed by the leadership of the ISHLT PH Council. |
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Authors:
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James C Fang; Teresa DeMarco; Michael M Givertz; Barry A Borlaug; Gregory D Lewis; J Eduardo Rame; Mardi Gomberg-Maitland; Srinivas Murali; Robert P Frantz; Dana McGlothlin; Evelyn M Horn; Raymond L Benza |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation Volume: 31 ISSN: 1557-3117 ISO Abbreviation: J. Heart Lung Transplant. Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-08-13 Completed Date: 2013-01-14 Revised Date: 2013-03-07 |
Medline Journal Info:
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Nlm Unique ID: 9102703 Medline TA: J Heart Lung Transplant Country: United States |
Other Details:
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Languages: eng Pagination: 913-33 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 International Society for Heart and Lung Transplantation. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Cardiovascular Medicine, Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, Cleveland, OH, USA. james.fang@uhhospitals.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Heart Diseases
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complications* Heart-Assist Devices Humans Hypertension, Pulmonary / diagnosis*, etiology, physiopathology, therapy* Mitral Valve Insufficiency / complications Mitral Valve Stenosis / complications Phosphodiesterase Inhibitors / therapeutic use Receptors, Endothelin / antagonists & inhibitors Vasodilator Agents / therapeutic use |
| Grant Support | |
ID/Acronym/Agency:
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K23-HL091106/HL/NHLBI NIH HHS; U01-HL084877/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Phosphodiesterase Inhibitors; 0/Receptors, Endothelin; 0/Vasodilator Agents |
| Comments/Corrections | |
Erratum In:
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J Heart Lung Transplant. 2013 Feb;32(2):275 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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