Document Detail

Workplace social capital and adherence to antihypertensive medication: a cohort study.
MedLine Citation:
PMID:  21931836     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: While hypertension is a common and treatable health problem, adherence to antihypertensive medication remains a challenge. This study examines the hypothesis that workplace social capital may influence adherence to antihypertensive medication among hypertensive employees.
METHODOLOGY/PRINCIPAL FINDINGS: We linked survey responses to nationwide pharmacy records for a cohort of 3515 hypertensive employees (mean age 53.9 years, 76% women) who required continuous antihypertensive drug therapy (the Finnish Public Sector study). A standard scale was used to measure workplace social capital from co-workers' assessments and self-reports in 2000-2004. Non-adherence to antihypertensive medication was determined based on the number of days-not-treated at the year following the survey using comprehensive prescription records. Negative binomial regression models were conducted adjusting for socio-demographic characteristics, duration of hypertension, behaviour-related risk factors, and co-morbid conditions. The overall rate of days-not-treated was 20.7 per person-year (78% had no days-not-treated). Higher age, obesity, and presence of somatic co-morbidities were all associated with better adherence, but this was not the case for co-worker-assessed or self-reported workplace social capital. The rate of days-not-treated was 19.7 per person-year in the bottom fourth of co-worker-assessed workplace social capital, compared to 20.4 in the top fourth. The corresponding rate ratio from the fully-adjusted model was 0.95 (95% confidence interval (CI) 0.58-1.56). In a subgroup of 907 new users of antihypertensive medication this rate ratio was 0.98 (95% CI 0.42-2.29).
CONCLUSIONS/SIGNIFICANCE: We found no consistent evidence to support the hypothesized effect of workplace social capital on adherence to drug therapy among employees with chronic hypertension.
Tuula Oksanen; Ichiro Kawachi; Anne Kouvonen; Etsuji Suzuki; Soshi Takao; Noora Sjösten; Marianna Virtanen; Jaana Pentti; Jussi Vahtera; Mika Kivimäki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-09-09
Journal Detail:
Title:  PloS one     Volume:  6     ISSN:  1932-6203     ISO Abbreviation:  PLoS ONE     Publication Date:  2011  
Date Detail:
Created Date:  2011-09-20     Completed Date:  2012-02-28     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  101285081     Medline TA:  PLoS One     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e24732     Citation Subset:  IM    
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MeSH Terms
Antihypertensive Agents / therapeutic use*
Hypertension / drug therapy*
Medication Adherence / statistics & numerical data*
Middle Aged
Social Support
Workplace / statistics & numerical data*
Grant Support
G0902037//Medical Research Council; G19/35//Medical Research Council; G8802774//Medical Research Council; RG/07/008/23674//British Heart Foundation
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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