Document Detail


Working memory for vibrotactile frequencies: comparison of cortical activity in blind and sighted individuals.
MedLine Citation:
PMID:  20162595     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In blind, occipital cortex showed robust activation to nonvisual stimuli in many prior functional neuroimaging studies. The cognitive processes represented by these activations are not fully determined, although a verbal recognition memory role has been demonstrated. In congenitally blind and sighted (10 per group), we contrasted responses to a vibrotactile one-back frequency retention task with 5-s delays and a vibrotactile amplitude-change task; both tasks involved the same vibration parameters. The one-back paradigm required continuous updating for working memory (WM). Findings in both groups confirmed roles in WM for right hemisphere dorsolateral prefrontal (DLPFC) and dorsal/ventral attention components of posterior parietal cortex. Negative findings in bilateral ventrolateral prefrontal cortex suggested task performance without subvocalization. In bilateral occipital cortex, blind showed comparable positive responses to both tasks, whereas WM evoked large negative responses in sighted. Greater utilization of attention resources in blind were suggested as causing larger responses in dorsal and ventral attention systems, right DLPFC, and persistent responses across delays between trials in somatosensory and premotor cortex. In sighted, responses in somatosensory and premotor areas showed iterated peaks matched to stimulation trial intervals. The findings in occipital cortex of blind suggest that tactile activations do not represent cognitive operations for nonverbal WM task. However, these data suggest a role in sensory processing for tactile information in blind that parallels a similar contribution for visual stimuli in occipital cortex of sighted.
Authors:
Harold Burton; Robert J Sinclair; Sachin Dixit
Related Documents :
10906375 - Organization of working memory within the human prefrontal cortex: a pet study of self-...
19175815 - Reduced activation in lateral prefrontal cortex and anterior cingulate during attention...
19628025 - Voxel-based morphometry reveals an association between aerobic capacity and grey matter...
23572205 - The speed and accuracy of perceptual decisions in a random-tone pitch task.
20938925 - Social recognition assay in the rat.
22021045 - Acquired self-control of insula cortex modulates emotion recognition and brain network ...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Human brain mapping     Volume:  31     ISSN:  1097-0193     ISO Abbreviation:  Hum Brain Mapp     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-19     Completed Date:  2011-01-28     Revised Date:  2013-04-10    
Medline Journal Info:
Nlm Unique ID:  9419065     Medline TA:  Hum Brain Mapp     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1686-701     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley-Liss, Inc.
Affiliation:
Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA. harold@pcg.wustl.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Attention / physiology
Blindness / physiopathology*
Brain Mapping
Cerebral Cortex / physiopathology*
Female
Humans
Magnetic Resonance Imaging
Male
Memory, Short-Term / physiology*
Middle Aged
Physical Stimulation
Psychomotor Performance / physiology
Touch / physiology*
Touch Perception / physiology*
Vibration
Grant Support
ID/Acronym/Agency:
NS37237/NS/NINDS NIH HHS; R01 NS037237/NS/NINDS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Intellectual abilities and white matter microstructure in development: a diffusion tensor imaging st...
Next Document:  Dynamic EEG-informed fMRI modeling of the pain matrix using 20-ms root mean square segments.