Document Detail


Work capacity of permanent residents of high altitude.
MedLine Citation:
PMID:  16764524     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Tibetan and Andean natives at altitude have allegedly a greater work capacity and stand fatigue better than acclimatized lowlanders. The principal aim of the present review is to establish whether convincing experimental evidence supports this belief and, should this be the case, to analyze the possible underlying mechanisms. The superior work capacity of high altitude natives is not based on differences in maximum aerobic power (V(O2 peak)), mL kg(-1)min(-1)). In fact, average V (O2 peak) of both Tibetan and Andean natives at altitude is only slightly, although not significantly, higher than that of Asian or Caucasian lowlanders resident for more than 1 yr between 3400 and 4700 m (Tibetans, n = 152, vs. Chinese Hans, n = 116: 42.4 +/- 3.4 vs. 39.2 +/- 2.6 mL kg(-1)min(-1), mean +/- SE; Andeans, n = 116, vs. Caucasians, n = 70: 47.1 +/- 1.7 vs. 41.6 +/- 1.2 mL kg(-1)min(-1)). However, compared to acclimatized lowlanders, Tibetans appear to be characterized by a better economy of cycling, walking, and running on a treadmill. This is possibly due to metabolic adaptations, such as increased muscle myoglobin content and antioxidant defense. All together, the latter changes may enhance the efficiency of the muscle oxidative metabolic machinery, thereby supporting a better prolonged submaximal performance capacity compared to lowlanders, despite equal V(O2 peak). With regard to Andeans, data on exercise efficiency is scanty and controversial and, at present, no conclusion can be drawn as to the origin of their superior performance.
Authors:
Claudio Marconi; Mauro Marzorati; Paolo Cerretelli
Related Documents :
8543384 - Estimation of the degree of acclimatization to high altitude by a rapid and simple phys...
17253634 - Ground use by northern muriquis (brachyteles hypoxanthus).
7631894 - Acclimatization to high altitude increase muscle sympathetic activity both at rest and ...
533244 - Ventilatory capacity among highland bods: a possible adaptive mechanism at high altitude.
10416554 - Ventilatory responses to exercise in patients with asymptomatic left ventricular dysfun...
2427844 - Celiprolol in the treatment of exercise induced angina pectoris.
Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  High altitude medicine & biology     Volume:  7     ISSN:  1527-0297     ISO Abbreviation:  High Alt. Med. Biol.     Publication Date:  2006  
Date Detail:
Created Date:  2006-06-12     Completed Date:  2006-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100901183     Medline TA:  High Alt Med Biol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  105-15     Citation Subset:  IM; S    
Affiliation:
IBFM-National Research Council Milano, Italy. claudio.marconi@ibfm.cnr.it
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acclimatization
Altitude*
Altitude Sickness*
Health Status*
Humans
Oxygen Consumption / physiology*
Peru
Physical Endurance / physiology
Tibet
Work Capacity Evaluation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  A connectionist computational model for epistemic and temporal reasoning.
Next Document:  Growth and development of Andean high altitude residents.