Document Detail

Work of breathing in anesthetized infants increases when a breathing system filter is used.
MedLine Citation:
PMID:  16918655     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: There are concerns that the inclusion of a pediatric heat and moisture exchange filter (HMEF) is in a breathing system may cause an unacceptable increase in the work of breathing. This study is the first study to objectively measure the increase in work of breathing in the infant population when an HMEF is added to the pediatric breathing circuit. METHODS: Ten patients weighing 3-8 kg were studied in a randomized crossover trial. Work of breathing was analyzed using the integral of pressure-volume loops. RESULTS: The median increase in the work of breathing associated with the addition of an HMEF was 279 mJ x min(-1) (95% CI, 165-903 mJ x min(-1)). This equates with a percentage increase of 43% (95% CI, 25-138%). CONCLUSIONS: Because of the substantial increase in the work of breathing with an HMEF attached to the tracheal tube, consideration should be given to alternative means of humidification and filtration during periods of spontaneous ventilation in small infants.
Graham T Bell; Kerryn M Martin; Stephen Beaton
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Paediatric anaesthesia     Volume:  16     ISSN:  1155-5645     ISO Abbreviation:  Paediatr Anaesth     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-08-21     Completed Date:  2007-01-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9206575     Medline TA:  Paediatr Anaesth     Country:  France    
Other Details:
Languages:  eng     Pagination:  939-43     Citation Subset:  IM    
Department of Anaesthetics, Royal Hospital for Sick Children, Dalnair St, Glasgow G3 8SJ, UK.
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MeSH Terms
Anesthesia / methods*
Work of Breathing / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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