| Women and omega-3 Fatty acids. | |
| | |
MedLine Citation:
|
PMID: 15385858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Omega-3 fatty acids (omega-3 FA) are constituents of the membranes of all cells in the body and are precursors of locally produced hormones, eicosanoids, which are important in the prevention and treatment of various diseases, especially in women. Omega-3 FA are of interest in some of the most common conditions affecting women. One mechanism underlying dysmenorrhea is a disturbed balance between antiinflammatory, vasodilator eicosanoids derived from omega-3 FA and proinflammatory, vasoconstrictor eicosanoids derived from omega-6 FA. Increased intake of omega-3 FA can reverse the symptoms in this condition by decreasing the amount of omega-6 FA in cell membranes. An increased prostacyclin/thromboxane ratio induced by omega-3 FA can facilitate pregnancy in women with infertility problems by increasing uterine blood flow. Supplementation with omega-3 FA during pregnancy lowers the risk of premature birth and can increase the length of pregnancy and birth weight by altering the balance of eicosanoids involved in labor and promote fetal growth by improving placental blood flow. Intake of omega-3 FA during pregnancy and breast feeding may facilitate the child's brain development. There is also some evidence that supplementation with omega-3 FA might help to prevent preeclampsia, postpartum depression, menopausal problems, postmenopausal osteoporosis, and breast cancer. Furthermore, because elevated triglyceride levels are associated with cardiovascular disease, especially in women; and because omega-3 FA have powerful effects on triglycerides, women in particular gain from an increased intake of these fatty acids. This is especially important in women receiving hormone therapy, which can increase triglyceride levels. The quality of the omega-3 FA preparation is important. It should have an appropriate antioxidant content not to induce lipid peroxidation, and its content of dioxin and polychlorinated biphenyls (PCBs) should be well below the established safe limit. |
| | |
Authors:
|
Pia Saldeen; Tom Saldeen |
Related Documents
:
|
19320698 - Opinions of non-pregnant new zealand women aged 16-40 years about the safety of alcohol... 17875358 - Prenatal alcohol exposure, cyp17 gene polymorphisms and fetal growth restriction. 7786898 - Effect of maternal ethanol consumption during pregnancy on the phospholipid molecular s... 16250418 - Prolonged exposure to angiotensin-converting enzyme inhibitors during pregnancy. fetal ... 9514138 - Transvaginal sonography of the forewaters in the assessment of amniotic fluid volume in... 10326878 - Correlation between fetal sex and human chorionic gonadotropin in peripheral maternal b... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Obstetrical & gynecological survey Volume: 59 ISSN: 0029-7828 ISO Abbreviation: Obstet Gynecol Surv Publication Date: 2004 Oct |
Date Detail:
|
Created Date: 2004-09-23 Completed Date: 2004-12-30 Revised Date: 2005-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0401007 Medline TA: Obstet Gynecol Surv Country: United States |
Other Details:
|
Languages: eng Pagination: 722-30; quiz 745-6 Citation Subset: IM |
Affiliation:
|
Department of Obstetrics and Gynecology, Malmö University Hospital, University of Lund, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Brain
/
embryology,
growth & development Breast Neoplasms / diet therapy, etiology, prevention & control Cardiovascular Diseases / prevention & control Depression, Postpartum / etiology Diabetes, Gestational / prevention & control Dysmenorrhea / etiology Fatty Acids, Omega-3 / administration & dosage, metabolism*, standards Fatty Acids, Omega-6 / adverse effects, metabolism Female Hormone Replacement Therapy / adverse effects Humans Infertility / etiology Menopause / metabolism Obstetric Labor, Premature / etiology Osteoporosis / prevention & control Pre-Eclampsia / prevention & control Pregnancy Triglycerides / blood Women's Health* |
| Chemical | |
Reg. No./Substance:
|
0/Fatty Acids, Omega-3; 0/Fatty Acids, Omega-6; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Exercise and urinary incontinence in women.
Next Document: Determination of maternal body composition in pregnancy and its relevance to perinatal outcomes.