| Wolfram's syndrome: a clinical, diagnostic, and interpretative contribution. | |
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MedLine Citation:
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PMID: 3490363 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Four cases (belonging to two different families) of Wolfram's syndrome (WS), a rare congenital disease characterized in its complete form by insulin-dependent diabetes mellitus, optic atrophy, diabetes insipidus, deafness, and dilation of the urinary tracts are presented, and a review of the literature is included. Three of four patients are characterized by HLA-DR2 haplotype, which is rare in IDDM. The neurodegenerative nature of some symptoms and the possible pathogenesis of diabetes mellitus connected with it are discussed. |
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Authors:
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C Blasi; F Pierelli; E Rispoli; M Saponara; E Vingolo; D Andreani |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Diabetes care Volume: 9 ISSN: 0149-5992 ISO Abbreviation: Diabetes Care Publication Date: 1986 Sep-Oct |
Date Detail:
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Created Date: 1986-12-16 Completed Date: 1986-12-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7805975 Medline TA: Diabetes Care Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 521-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Diabetes Mellitus, Type 1
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complications,
genetics Female HLA-DR Antigens / analysis HLA-DR2 Antigen Haplotypes Humans Male Pedigree Wolfram Syndrome / diagnosis, genetics, physiopathology* |
| Chemical | |
Reg. No./Substance:
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0/HLA-DR Antigens; 0/HLA-DR2 Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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