Document Detail

The Wisconsin Card Sorting Test discriminates schizophrenic patients and their siblings.
MedLine Citation:
PMID:  8398941     Owner:  NLM     Status:  MEDLINE    
The following report is an evaluation of the performances of 35 schizophrenic patients and 35 of their siblings on the Wisconsin Card Sorting Test (WCST), a neuropsychological test considered sensitive to frontal lobe functioning. Thirty five normal subjects matched for age and education were the comparison group. The purpose of this study was to examine the relationship of the neurofunctional basis for schizophrenia to its familiar occurrence. Non-schizophrenic siblings of schizophrenic patients did not perform significantly different from normal subjects on the WCST; however, schizophrenic patients performed significantly worse than both their siblings and normal subjects. These results indicate that WCST dysfunction seems to be a characteristic related to the presence of the disease and that non-genetic factors could contribute to the WCST pathological profile.
S Scarone; M Abbruzzese; O Gambini
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Schizophrenia research     Volume:  10     ISSN:  0920-9964     ISO Abbreviation:  Schizophr. Res.     Publication Date:  1993 Aug 
Date Detail:
Created Date:  1993-11-17     Completed Date:  1993-11-17     Revised Date:  2010-09-02    
Medline Journal Info:
Nlm Unique ID:  8804207     Medline TA:  Schizophr Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  103-7     Citation Subset:  IM    
Department of Biomedical and Technological Sciences, University of Milan Medical School, Italy.
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MeSH Terms
Color Perception
Discrimination Learning*
Mental Recall
Neuropsychological Tests*
Pattern Recognition, Visual*
Schizophrenia / diagnosis,  genetics*
Schizophrenic Psychology*

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