Document Detail


Wiring and rewiring of the retinogeniculate synapse.
MedLine Citation:
PMID:  21558027     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The formation and refinement of synaptic circuits are areas of research that have fascinated neurobiologists for decades. A recurrent theme seen at many CNS synapses is that neuronal connections are at first imprecise, but refine and can be rearranged with time or with experience. Today, with the advent of new technologies to map and monitor neuronal circuits, it is worthwhile to revisit a powerful experimental model for examining the development and plasticity of synaptic circuits--the retinogeniculate synapse.
Authors:
Y Kate Hong; Chinfei Chen
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current opinion in neurobiology     Volume:  21     ISSN:  1873-6882     ISO Abbreviation:  Curr. Opin. Neurobiol.     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-05-11     Completed Date:  2011-09-12     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  9111376     Medline TA:  Curr Opin Neurobiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  228-37     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Neurology, F.M. Kirby Neurobiology Center, Children's Hospital, Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, United States.
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MeSH Terms
Descriptor/Qualifier:
Animals
Geniculate Bodies / physiology,  ultrastructure
Humans
Neurogenesis / physiology*
Neuronal Plasticity / physiology*
Retina / physiology,  ultrastructure
Synapses / physiology*,  ultrastructure
Grant Support
ID/Acronym/Agency:
P01 HD18655/HD/NICHD NIH HHS; R01 EY013613/EY/NEI NIH HHS; R01 EY013613-06A1/EY/NEI NIH HHS
Comments/Corrections

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