Document Detail

Wine drinking is associated with increased heart rate variability in women with coronary heart disease.
MedLine Citation:
PMID:  15710709     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To test the hypothesis that alcohol consumption is positively related to heart rate variability (HRV) in women with coronary heart disease (CHD) and therefore that cardiac autonomic activity is potentially implicated in the mediation of the favourable effects of moderate drinking.
DESIGN, SETTINGS, AND PATIENTS: Cross sectional study of female patients who survived hospitalisation for acute myocardial infarction or underwent a revascularisation procedure, percutaneous transluminal coronary angioplasty, or coronary artery bypass grafting.
MAIN OUTCOME MEASURES: Ambulatory 24 hour ECG was recorded during normal activities. The mean of the standard deviations of all normal to normal intervals for all five minute segments of the entire recording (SDNNI) and the following frequency domain parameters were assessed: total power, high frequency power, low frequency power, and very low frequency power. A standardised questionnaire evaluated self reported consumption of individual alcoholic beverage types: beer, wine, and spirits. Other clinical characteristics, such as age, body mass index, smoking habits, history of diabetes mellitus, menopausal status, educational status, and treatment, were also assessed.
RESULTS: Wine intake was associated with increased HRV in both time and frequency domains independently of other clinical covariates (for example, ln SDNNI was 3.89 among wine drinkers v 3.59 among wine non-drinkers in the multivariate model; p = 0.014). In contrast, consumption of beer and spirits and the total amount of alcohol consumed did not relate significantly to any of the HRV parameters.
CONCLUSION: Intake of wine, but not of spirits or beer, is positively and independently associated with HRV in women with CHD. These results may contribute to the understanding of the complex relation between alcohol consumption and CHD.
I Janszky; M Ericson; M Blom; A Georgiades; J-O Magnusson; H Alinagizadeh; S Ahnve
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  91     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-02-15     Completed Date:  2005-03-07     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  England    
Other Details:
Languages:  eng     Pagination:  314-8     Citation Subset:  AIM; IM    
Preventive Medicine, Department of Public Health Sciences, Karolinska Institute, and Centre of Public Health, Stockholm County Council, Stockholm, Sweden.
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MeSH Terms
Age Factors
Alcohol Drinking*
Angioplasty, Balloon, Coronary / methods
Coronary Artery Bypass / methods
Coronary Disease / physiopathology*
Cross-Sectional Studies
Electrocardiography / methods
Heart Rate / physiology
Middle Aged
Myocardial Infarction / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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