Document Detail


Wilson disease with an initial manifestation of polyneuropathy.
MedLine Citation:
PMID:  16216950     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Recognition of Wilson disease (WD) is sometimes difficult because of its diverse manifestations. Peripheral neuropathy is rarely reported in the context of WD. OBJECTIVE: To report an unusual patient with WD whose initial manifestation was peripheral neuropathy. DESIGN: Case report. SETTING: Neurology department in a tertiary referral center. METHOD: Personal observation. RESULT: A 17-year-old man, who was eventually diagnosed with WD, was initially seen with polyneuropathy at least 6 months prior to developing more typical symptoms of WD. Electrophysiological and pathological studies suggested a neuropathy of mixed type. Treatment for WD resulted in clinical and electrophysiological improvement. CONCLUSION: Wilson disease may initially appear as a treatable polyneuropathy.
Authors:
Keun-Hwa Jung; Tae-Beom Ahn; Beom S Jeon
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of neurology     Volume:  62     ISSN:  0003-9942     ISO Abbreviation:  Arch. Neurol.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-11     Completed Date:  2005-11-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372436     Medline TA:  Arch Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1628-31     Citation Subset:  AIM; IM    
Affiliation:
Department of Neurology and Clinical Research Institute, Seoul National University Hospital, Kyung Hee University Hospital, Seoul, South Korea.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Brain / pathology
Electrophysiology
Hepatolenticular Degeneration / complications*,  physiopathology*
Humans
Magnetic Resonance Imaging
Male
Polyneuropathies / etiology*,  pathology
Sural Nerve / pathology

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