Document Detail

Wilm's tumour, hypospadias, and cryptorchidism in twins.
MedLine Citation:
PMID:  15524     Owner:  NLM     Status:  MEDLINE    
Twin boys, both of whom had hypospadias and bilateral cryptorchidism, each developed a left-sided Wilms's tumour. The first twin was found to have an advanced multifocal tumour at the age of 15 months and died with local recurrence and pulmonary metastases. The diagnosis was made in the second twin one month later and at nephrectomy the tumour was found to be encapsulated without metastases; he is disease-free 12-years later. Although the histological appearances were similar in each twin, the tumours did not develop at the same rate and did not show the 'mirror-image' pattern suggested for embryonal tumours in identical twins.
J V Bond
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  52     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1977 Mar 
Date Detail:
Created Date:  1977-05-25     Completed Date:  1977-05-25     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  243-5     Citation Subset:  IM    
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MeSH Terms
Cryptorchidism / complications
Diseases in Twins*
Hypospadias / complications
Wilms Tumor / complications*,  genetics

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