| Willingness to participate in cardiac trials. | |
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MedLine Citation:
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PMID: 14724396 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The elderly, women, and minorities are all less likely to be enrolled in randomized clinical trials (RCTs). Whether differential patient interest in RCTs contributes to these disparities is unclear. The authors surveyed 660 patients willingness to consider two potential cardiac RCTs of medical therapy vs. percutaneous coronary angioplasty or coronary artery bypass surgery, respectively. The cohorts mean age was 67 years (43% aged >or=70 years; 35% women; and 28% nonwhite). Compared with younger patients, those aged >or=70 years were equal or more likely to consider both the percutaneous coronary angioplasty (46% vs. 41%) and coronary artery bypass surgery RCTs (35% vs. 31%). Race also had no significant impact on trial enrollment, yet women were significantly less likely than men to participate in either RCT. In conclusion, patient willingness to consider RCT participation does not explain underenrollment of elderly and minority patients. Women, however, were more reluctant to consider RCTs, an area requiring further study. |
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Authors:
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Eric D Peterson; Barbara L Lytle; Mimi S Biswas; Laura Coombs |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of geriatric cardiology Volume: 13 ISSN: 1076-7460 ISO Abbreviation: Am J Geriatr Cardiol Publication Date: 2004 Jan-Feb |
Date Detail:
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Created Date: 2004-01-15 Completed Date: 2004-05-20 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9215283 Medline TA: Am J Geriatr Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 11-5 Citation Subset: IM |
Affiliation:
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The Outcomes Research and Assessment Group, The Duke Clinical Research Institute, Durham, NC 27710, USA. peter016@mc.duke.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Aged Angioplasty, Transluminal, Percutaneous Coronary Cohort Studies Coronary Artery Bypass Coronary Disease / therapy* Cultural Diversity Female Humans Male Middle Aged Patient Participation / psychology*, statistics & numerical data Patient Selection* Randomized Controlled Trials as Topic / statistics & numerical data* Sex Factors Treatment Refusal / psychology, statistics & numerical data Women's Health |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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