Document Detail

Will simultaneous measurement of E/e' index facilitate the non-invasive assessment of left ventricular filling pressure in patients with non-valvular atrial fibrillation?
MedLine Citation:
PMID:  20022868     Owner:  NLM     Status:  MEDLINE    
AIMS: The ratio of early transmitral flow velocity (E) to early diastolic mitral annular velocity (e') was applied as a non-invasive index to assess left ventricular filling pressure (LVFP). However, the reliability of E/e' was undermined in patients with atrial fibrillation (AF). Recently, a novel method entitled 'dual Doppler' was established, which allows simultaneous recording and display of E and e'. Our study investigates whether the dual-Doppler method improves the reliability of E/e' in AF patients. METHODS AND RESULTS: Forty-nine patients with non-valvular AF underwent conventional echocardiography, dual-Doppler echocardiography, and cardiac catheterization within 4 h. Of 22 patients (45%c) with increased LVFP (>15 mmHg), higher E/e' measured by both conventional tissue Doppler imaging (TDI) and dual-Doppler method was observed. Conventional echocardiographic variables were correlated with LVFP (E/e'(sep), r = 0.404, E/e'(lat), r = 0.487), but E/e' measured synchronously in the dual-Doppler mode yielded a better correlation (E/e'(synchronous sep), r = 0.754, E/e'(synchronous lat), r = 0.765). The intra- and interobserver variability of the dual-Doppler method was significantly lower than the conventional TDI method. CONCLUSION: Good correlations were found between E/e'' and LVFP in patients with AF, particularly in the dual-Doppler mode. E/e' measured by the dual-Doppler method can therefore be applied to assess diastolic dysfunction in AF patients.
Chen Li; Juqian Zhang; Can Zhou; Liwei Huang; Hong Tang; Li Rao
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-12-17
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  11     ISSN:  1532-2114     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-08     Completed Date:  2010-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  296-301     Citation Subset:  IM    
Department of Cardiology, West China Hospital of Sichuan University, 37 Guo Xue Xiang, Chengdu, Sichuan 610041, PR China.
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MeSH Terms
Atrial Fibrillation / physiopathology*,  ultrasonography
Blood Pressure / physiology*
Echocardiography / methods
Echocardiography, Doppler, Color / methods
Middle Aged
Observer Variation
Sensitivity and Specificity
Stroke Volume
Ventricular Dysfunction, Left / physiopathology*,  ultrasonography

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