Document Detail

Widespread intranuclear neuronal corpuscles (Marinesco bodies) associated with a familial spinal degeneration with cranial and peripheral nerve involvement.
MedLine Citation:
PMID:  225694     Owner:  NLM     Status:  MEDLINE    
Widespread intranuclear, paranucleolar, acidophilic corpuscles, known as Marinesco bodies, were found in association with degeneration of the posterior columns of ting at the age of 45 years. Neurological examination of his sister (aged 51 years) inciates that she is suffering from the same diseases. The cases appear to belong to the predominantly spinal form of spino-cerebellar degenerations or Friedreich's ataxia. This report, which includes an electron microscope examination, considers the pathological significance of Marinesco bodies.
I Janota
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuropathology and applied neurobiology     Volume:  5     ISSN:  0305-1846     ISO Abbreviation:  Neuropathol. Appl. Neurobiol.     Publication Date:  1979 Aug 
Date Detail:
Created Date:  1979-11-29     Completed Date:  1979-11-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7609829     Medline TA:  Neuropathol Appl Neurobiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  311-7     Citation Subset:  IM    
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MeSH Terms
Brain Stem / pathology
Cell Nucleus / ultrastructure*
Cranial Nerves / pathology
Ganglia, Spinal / pathology
Inclusion Bodies / ultrastructure*
Peripheral Nervous System Diseases / genetics*
Spinal Cord / pathology
Spinal Cord Diseases / genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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