| Widespread cutaneous necrosis as the initial manifestation of the antiphospholipid antibody syndrome. | |
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MedLine Citation:
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PMID: 7562777 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe a patient with the acute onset of widespread cutaneous necrosis as the initial manifestation of the antiphospholipid antibody syndrome (APS). The patient was effectively treated with corticosteroids and anticoagulants, however extensive skin grafting was eventually required. We review 6 other reported cases and discuss the various underlying etiologies of vascular thrombosis resulting in cutaneous necrosis. Early recognition and treatment of the APS may limit the extent of thrombotic complications that can result in tissue necrosis. |
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Authors:
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M L Abernethy; J L McGuinn; J P Callen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of rheumatology Volume: 22 ISSN: 0315-162X ISO Abbreviation: J. Rheumatol. Publication Date: 1995 Jul |
Date Detail:
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Created Date: 1995-11-22 Completed Date: 1995-11-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7501984 Medline TA: J Rheumatol Country: CANADA |
Other Details:
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Languages: eng Pagination: 1380-3 Citation Subset: IM |
Affiliation:
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Department of Medicine, University of Louisville School of Medicine, KY, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adrenal Cortex Hormones / therapeutic use Anticoagulants / therapeutic use Antiphospholipid Syndrome / diagnosis, drug therapy, pathology* Female Humans Middle Aged Necrosis / prevention & control Skin / pathology* |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anticoagulants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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