Document Detail


Why don't we have more effective treatment for keloids?
MedLine Citation:
PMID:  20887703     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Numerous treatment modalities have been used to treat keloids and hypertrophic scars, but optimal treatment has not yet been established. The failure of achieving better therapeutic results in treating keloids highlights the essential problem that the pathogenetic mechanisms causing keloids remain unclear. Increased understanding at the molecular level will lead to the development of new therapies. Prevention is the first rule in keloid therapy. Conventional and experimental therapeutic approaches are presented in this review but further investigation is needed in relation to safety, adverse effects, and therapeutic efficacy. Because of the high recurrence rate of keloid scars, a follow-up period of at least 1 year is required to enable the start of treatment of recurrences as expediently as possible and to evaluate long-term success.
Authors:
Romana Ceović; Jasna Lipozenčić; Zrinka Bukvić Mokos; Daška Stulhofer Buzina; Krešimir Kostović
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta dermatovenerologica Croatica : ADC     Volume:  18     ISSN:  1847-6538     ISO Abbreviation:  Acta Dermatovenerol Croat     Publication Date:  2010  
Date Detail:
Created Date:  2010-10-04     Completed Date:  2011-01-25     Revised Date:  2012-08-31    
Medline Journal Info:
Nlm Unique ID:  9433781     Medline TA:  Acta Dermatovenerol Croat     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  195-200     Citation Subset:  IM    
Affiliation:
University Hospital Center Zagreb, Department of Dermatology and Venereology, School of Medicine, University of Zagreb, Šalata 4, Zagreb, Croatia. romana.ceovic@zg.htnet.hr
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MeSH Terms
Descriptor/Qualifier:
Cicatrix, Hypertrophic / diagnosis,  therapy
Humans
Keloid / diagnosis,  etiology,  physiopathology,  therapy*
Laser Therapy

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