Document Detail

Whole lung lavage for pulmonary alveolar proteinosis.
MedLine Citation:
PMID:  20539770     Owner:  NLM     Status:  PubMed-not-MEDLINE    
A 26-year-old male presented with complaints of dry cough of six months and progressive breathlessness of three months duration. He was coughing out milky white sputum for two months and had lost 12 kg weight in two months. He had an evening rise in temperature of one month duration. Clinically, the patient was in respiratory distress and the respiratory system examination revealed bilateral velcro crackles. High resolution computed tomography chest showed bilateral diffuse reticulonodular opacities and "Crazy Paving" pattern suggestive of alveolar proteinosis. Broncho alveolar lavage showed eosinophilic granular material, which was periodic acid-Schiff positive. Open lung biopsy was done to confirm the diagnosis and the histopathologic examination revealed eosinophilic secretions with granular appearance suggestive of pulmonary alveolar proteinosis. Subsequently, patient underwent bilateral sequential whole lung lavage under general anesthesia. Patient showed marked clinical and radiological improvement after sequential whole lung lavage.
S Jayaraman; A R Gayathri; P Senthil Kumar; Rajeev Santosham; Rajan Santosham; R Narasimhan
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lung India : official organ of Indian Chest Society     Volume:  27     ISSN:  0974-598X     ISO Abbreviation:  Lung India     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-06-11     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  8405380     Medline TA:  Lung India     Country:  India    
Other Details:
Languages:  eng     Pagination:  33-6     Citation Subset:  -    
Department of Respiratory Medicine, Apollo Hospitals, Chennai - 600 006, India.
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