Document Detail


Whole-body computed tomography for multiple traumas using a triphasic injection protocol.
MedLine Citation:
PMID:  18270712     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate a triphasic injection protocol for whole-body multidetector computed tomography (MDCT) in patients with multiple trauma. Fifty consecutive patients (41 men) were examined. Contrast medium (300 mg/mL iodine) was injected starting with 70 mL at 3 mL/s, followed by 0.1 mL/s for 8 s, and by another bolus of 75 mL at 4 mL/s. CT data acquisition started 50 s after the beginning of the first injection. Two experienced, blinded readers independently measured the density in all major arteries, veins, and parenchymatous organs. Image quality was assessed using a five-point ordinal rating scale and compared to standard injection protocols [n = 25 each for late arterial chest, portovenous abdomen, and MDCT angiography (CTA)]. With the exception of the infrarenal inferior caval vein, all blood vessels were depicted with diagnostic image quality using the multiple-trauma protocol. Arterial luminal density was slightly but significantly smaller compared to CTA (P < 0.01). Veins and parenchymatous organs were opacified significantly better compared to all other protocols (P < 0.01). Arm artifacts reduced the density of spleen and liver parenchyma significantly (P < 0.01). Similarly high image quality is achieved for arteries using the multiple-trauma protocol compared to CTA, and parenchymatous organs are depicted with better image quality compared to specialized protocols. Arm artifacts should be avoided.
Authors:
Christos Loupatatzis; Sebastian Schindera; Jan Gralla; Hanno Hoppe; Jan Bittner; Ralph Schröder; Sudesh Srivastav; Harald Marcel Bonel
Publication Detail:
Type:  Journal Article     Date:  2008-02-13
Journal Detail:
Title:  European radiology     Volume:  18     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-05-08     Completed Date:  2008-10-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1206-14     Citation Subset:  IM    
Affiliation:
Institute for Diagnostic, Interventional and Pediatric Radiology, Inselspital Berne, Freiburgstrasse 10, CH-3010 Berne, Switzerland.
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MeSH Terms
Descriptor/Qualifier:
Adult
Analysis of Variance
Contrast Media / administration & dosage*
Female
Humans
Injections, Intravenous
Iohexol / administration & dosage,  analogs & derivatives*
Male
Middle Aged
Multiple Trauma / radiography*
Retrospective Studies
Tomography, X-Ray Computed / methods*
Whole Body Imaging*
Chemical
Reg. No./Substance:
0/Contrast Media; 66108-95-0/Iohexol; 73334-07-3/iopromide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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