| Whole-body PET/CT-colonography: a possible new concept for colorectal cancer staging. | |
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MedLine Citation:
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PMID: 17387540 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Colorectal cancer (CRC) is a leading cause of death, and necessitates a conjointly performed staging. Until now, a multi-step-examination including optical colonoscopy, cross-sectional and functional imaging is recommended. However, a single examination for whole-body staging with a dedicated CRC staging protocol is desirable. Thus, we developed and evaluated a combined whole-body PET/CT-colonography protocol for dedicated CRC staging in routine clinical use. METHODS: We integrated CT-colonography into a whole-body PET/CT protocol to achieve a specific "all-in-one" examination for patients suspected of having CRC. After oral and rectal bowel distension, PET/CT-colonography has been performed in 55 patients. All patients had optical colonoscopy one day before PET/CT. PET/CT data sets were evaluated concerning detection and evaluation of colorectal tumour sites, lymph nodes and distant metastases; these results were compared to the results of CT-colonography alone. Surgical resection and/or biopsy served as standards of reference in all patients. RESULTS: All examinations were fully diagnostic and well tolerated by the patients. PET/CT-colonography showed highly accurate results for overall TNM-evaluation and was significantly more accurate than CT-colonography alone. CONCLUSIONS: Staging patients with whole-body PET/CT-colonography is technically feasible and accurate. Patients with incomplete colonoscopy or potential synchronous bowel lesions might benefit from this approach. |
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Authors:
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Sonja Kinner; Gerald Antoch; Andreas Bockisch; Patrick Veit-Haibach |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Abdominal imaging Volume: 32 ISSN: 0942-8925 ISO Abbreviation: Abdom Imaging Publication Date: 2007 Sep-Oct |
Date Detail:
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Created Date: 2007-10-16 Completed Date: 2008-04-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9303672 Medline TA: Abdom Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 606-12 Citation Subset: IM |
Affiliation:
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Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany. Sonja.Kinner@uni-due.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy Colonic Neoplasms / diagnosis, pathology Colonography, Computed Tomographic / methods* Colorectal Neoplasms / diagnosis*, pathology* Humans Image Processing, Computer-Assisted Neoplasm Staging / methods Positron-Emission Tomography / methods* Rectal Neoplasms / diagnosis, pathology Reproducibility of Results Whole Body Imaging / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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