Document Detail

Whole-body arsenic concentrations in rainbow trout during acute exposure to arsenate.
MedLine Citation:
PMID:  1282875     Owner:  NLM     Status:  MEDLINE    
This research explored the influence of temperature and waterborne arsenate exposure level on the whole-body arsenic (As) concentration in rainbow trout (Oncorhynchus mykiss) at loss of equilibrium (LOE), an acute toxicity endpoint. The mean median times (ET50s) to LOE for fish exposed to 120 mg arsenate liter-1 at 5 degrees C, as well as 60 and 120 mg liter-1 at 15 degrees C were 56.8, 210, and 34.8 hr, respectively. Despite the differences in ET50, the fish showed respective mean (SE) whole-body As concentrations of 8.6 (0.3), 8.1 (0.6), and 8.6 (0.4) micrograms As g-1, values which were not significantly different. Fish exposed to 240 mg arsenate liter-1 at 5 degrees C, which had a LOE ET50 of 32.2 hr, were observed to have a mean (SE) whole-body arsenic concentration of 13.5 micrograms g-1, significantly higher than the levels in fish from all other treatments. A 3-hr delay between LOE and sampling did not significantly alter whole-body As concentration. The results are discussed in terms of the utility of using whole-body As concentrations to interpret the impacts of arsenate on fish populations in the field.
S M McGeachy; D G Dixon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Ecotoxicology and environmental safety     Volume:  24     ISSN:  0147-6513     ISO Abbreviation:  Ecotoxicol. Environ. Saf.     Publication Date:  1992 Dec 
Date Detail:
Created Date:  1993-02-17     Completed Date:  1993-02-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7805381     Medline TA:  Ecotoxicol Environ Saf     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  301-8     Citation Subset:  IM    
Department of Biology, University of Waterloo, Ontario, Canada.
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MeSH Terms
Arsenates / pharmacokinetics,  toxicity*
Body Burden
Lethal Dose 50
Postural Balance / drug effects*
Trout / metabolism*
Water Pollutants, Chemical / pharmacokinetics,  toxicity
Reg. No./Substance:
0/Arsenates; 0/Water Pollutants, Chemical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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