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Whole blood transfusion in the treatment of an acute organophosphorus poisoning - a case report.
MedLine Citation:
PMID:  21873952     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: Organophosphorus compounds (OP) are a group of substances used in agriculture as pesticides and are also used as military poisoning agents (MPA). Intoxication by these agents may cause severe systemic disturbances related to both the exposure time and lethal agent concentration. Toxic effects result from an excess of the endogenous neurotransmitter, acetylcholine (ACh), because decomposition of Ach by cholinesterases is blocked by OP.<br /> Case Report: The authors describe a case in which an acute OP poisoning was managed both conventionally and with cholinesterase substitution by blood transfusion.<br /> Conclusions: Whole blood transfusion could be beneficial in the treatment of these life-threatening medical conditions.<br />
Authors:
Stan Ryniak; Piotr Harbut; Waldemar Goździk; Janusz Sokołowski; Przemysław Paciorek; Joanna Hałas
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical science monitor : international medical journal of experimental and clinical research     Volume:  17     ISSN:  1643-3750     ISO Abbreviation:  Med. Sci. Monit.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-08-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9609063     Medline TA:  Med Sci Monit     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  CS109-111     Citation Subset:  IM    
Affiliation:
Department of Anaesthesiology and Intensive Therapy, Karolinska University Hospital, Stockholm, Sweden.
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