| Whole blood transfusion in small animals: indications and effects. | |
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MedLine Citation:
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PMID: 21670882 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Transfusion therapy is a major resource that can improve the patient's capability to overcome the underlying disease. However, the effects of whole blood infusion, and how they affect the patient's outcome, are not yet clear. For this study, a protocol was developed in order to monitor a group of 15 animals (9 dogs, 6 cats) that received a total of 19 transfusions; 3 animals received more than one transfusion each. The most common indications for blood transfusion included acute blood loss (47%), coagulopathy (33%) and other anaemias (20%). The mean pre-transfusion packed cell volume (PCV) of animals with acute blood loss (18%) was higher than in the group of coagulopathy (15%) or other anaemias (15%). The survival rates at 6 days after transfusion were greater in the coagulopathy (80.0%) and other anaemias (66.7%) than in the group of acute blood loss (42.9%). After transfusion, pulse rate ( p <0.01) and platelet count ( p <0.05) decreased significantly, and there was a significant increase in body temperature of the animals that suffered from hypothermia before the transfusion ( p <0.05). Overall survival was predictable based upon posttransfusion body temperature, observed PCV change, the difference between the obtained and the calculated PCV, and administered transfusion volume ( p <0.05). |
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Authors:
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Luís F Godinho-Cunha; Rui M R F Ferreira; Ana C Silvestre-Ferreira |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Anais da Academia Brasileira de Ciências Volume: 83 ISSN: 1678-2690 ISO Abbreviation: An. Acad. Bras. Cienc. Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-06-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7503280 Medline TA: An Acad Bras Cienc Country: Brazil |
Other Details:
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Languages: eng Pagination: 611-7 Citation Subset: IM |
Affiliation:
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Departamento de Ciências Veterinárias, Hospital Veterinário, Universidade de Trás-os-Montes e Alto Douro Quinta de Prados, Vila Real, Portugal, 5001-801. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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