Document Detail


White sponge nevus (leukoedema exfoliativum mucosae oris): ultrastructural observations.
MedLine Citation:
PMID:  179037     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Biopsy specimens from the oral lesions of white sponge nevus (WSN) in thirteen patients were analyzed by electron microscopy. Several marked deviations from the normal ultrastructure were recorded. Similarities and dissimilarities with other hereditary disturbances affecting the epithelium are discussed. Profound disturbance of the tonofilament system, with atypical aggregation of tonofilaments, was observed. Odland bodies, which are numerous in keratinized epithelia and are extruded into the intercellular space prior to the exfoliation of the surface cells, were also abundant in the WSN specimens. Very little material originating from Odland bodies appears, however, in the intercellular space in WSN. Presumably, the Odland bodies fail to properly function enzymatically in WSN.
Authors:
L Frithiof; J Bánóczy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, and oral pathology     Volume:  41     ISSN:  0030-4220     ISO Abbreviation:  Oral Surg. Oral Med. Oral Pathol.     Publication Date:  1976 May 
Date Detail:
Created Date:  1976-08-02     Completed Date:  1976-08-02     Revised Date:  2000-12-18    
Medline Journal Info:
Nlm Unique ID:  0376406     Medline TA:  Oral Surg Oral Med Oral Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  607-22     Citation Subset:  D; IM    
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MeSH Terms
Descriptor/Qualifier:
Basement Membrane / ultrastructure
Connective Tissue / ultrastructure
Cytoplasm / ultrastructure
Epithelium / ultrastructure
Inclusion Bodies / ultrastructure
Leukoedema, Oral / congenital*,  pathology
Mouth Diseases / congenital*
Mouth Mucosa / ultrastructure*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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