Document Detail

White matter injury in preterm infants: could human milk play a role in its prevention?
MedLine Citation:
PMID:  23532026     Owner:  NLM     Status:  In-Data-Review    
Human milk has been found to be beneficial for the development of all newborns. It is protective during the development of the gastrointestinal tract, important in neurologic development, immune system function, and nourishment. Human milk has a number of components that aid in the anti-inflammatory process and free radical reduction and is a building block for neurologic development. Cerebral white matter injury is a common occurrence in preterm infants. Results of this injury can be seen into early childhood and throughout the life of the individual. White matter injury most frequently occurs because of hypoxia and the inflammatory process, which often results in the injury of myelinating oligodendrites. This article proposes the potential importance of human milk in slowing and preventing cerebral white matter injury because of the components in human milk that affect the inflammatory and free radical reduction processes. It also proposes its ability to provide nutrients essential to myelin development.
Francesca O Kotey; Diane L Spatz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in neonatal care : official journal of the National Association of Neonatal Nurses     Volume:  13     ISSN:  1536-0911     ISO Abbreviation:  Adv Neonatal Care     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101125644     Medline TA:  Adv Neonatal Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  89-94     Citation Subset:  IM    
University of Pennsylvania School of Nursing, Philadelphia.
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