Document Detail

White coat hypertension in children: not rare and not benign?
MedLine Citation:
PMID:  20409984     Owner:  NLM     Status:  In-Data-Review    
The clinical significance of white coat hypertension (WCH) remains uncertain. We aimed to evaluate the target organ damage (TOD) in children with essential hypertension (HTN) and WCH. We retrospectively analyzed the body mass index (BMI) and ambulatory blood pressure monitoring (ABPM) in 183 untreated children aged 5 to 19 years who were referred for assessment of hypertension and had secondary hypertension ruled out. Left ventricular mass index (LVMi) and carotid intima media thickness (CIMT) were analyzed in a subset of 106 children. WCH was found in 54/183 children (29.5%) who had normal mean arterial pressure (MAP), MAP load, and MAP day/night ratio. However, the mean+/-SD LVMi (g/m(2.7)) was identical in HTN and WCH patients (38.2+/-10.9 vs. 37.0+/-11.3, P=.59); it exceeded the 95th percentile in 40% HTN and 36% WCH patients (NS). The mean CIMT was significantly higher compared with normal, but not different between HTN and WCH; it exceeded the 95th percentile in 26% HTN and 29% WCH patients. WCH was found in up to 30% of children referred for HTN. Patients with WCH have TOD comparable to that found in HTN patients despite similar BMI, significantly lower average BP and BP load and a well-preserved BP dipping pattern.
Mieczyslaw Litwin; Anna Niemirska; Marcel Ruzicka; Janusz Feber
Related Documents :
7411354 - Treatment of choledochal cyst by excision.
22497554 - Olmesartan medoxomil in children and adolescents with hypertension†: profile report.
10526054 - Mucosal cell proliferation activity of the gallbladder in children with anomalous arran...
7602724 - Feeding-induced changes in energy expenditure in children with cystic fibrosis.
19202124 - Orthopaedic conditions in the newborn.
18037944 - Reduced intensity conditioning and allogeneic stem cell transplantation in childhood ma...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the American Society of Hypertension : JASH     Volume:  3     ISSN:  1933-1711     ISO Abbreviation:  J Am Soc Hypertens     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2010-04-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101312518     Medline TA:  J Am Soc Hypertens     Country:  United States    
Other Details:
Languages:  eng     Pagination:  416-23     Citation Subset:  -    
Department of Nephrology and Arterial Hypertension, The Children's Memorial Health Institute, Warsaw, Poland; Department of Research, The Children's Memorial Health Institute, Warsaw, Poland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Costs associated with cardiovascular events in patients with hypertension in US managed care setting...
Next Document:  Nonlinear trend estimation of the ventricular repolarization segment for T-wave alternans detection.