| White Matter Lesions Progression in Migraine with Aura: A Clinical and MRI Longitudinal Study. | |
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MedLine Citation:
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PMID: 22268442 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To prospectively evaluate longitudinal changes in white matter lesions (WMLs) in migraineurs with aura, by magnetic resonance imaging (MRI), and to correlate WMLs modifications with patients' clinical characteristics. METHODS: Forty-one consecutive migraineurs with aura were followed for a mean time of 33.2 months. Patients underwent MRI at baseline and follow-up and were evaluated for cerebrovascular risk factors. Presence of WMLs on MRI was assessed by two neuroradiologists. RESULTS: WMLs were present in 26 subjects (63.4%) at baseline MRI. At follow-up a total of 8 patients had new WMLs (19.5%). There was a significant correlation between aura duration and number of new WMLs, and between the number of migraine attacks with aura and new WMLs. CONCLUSIONS: Our study demonstrates that in migraine with aura WMLs number can progress over time and suggests an association between aura features and WMLs progression. Studies with a higher number of patients are required to confirm these findings. J Neuroimaging 2012;XX:1-6. |
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Authors:
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Lavinia Dinia; Laura Bonzano; Beatrice Albano; Cinzia Finocchi; Massimo Del Sette; Laura Saitta; Lucio Castellan; Carlo Gandolfo; Luca Roccatagliata |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-23 |
Journal Detail:
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Title: Journal of neuroimaging : official journal of the American Society of Neuroimaging Volume: - ISSN: 1552-6569 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9102705 Medline TA: J Neuroimaging Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 by the American Society of Neuroimaging. |
Affiliation:
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From the Department of Neurosciences, Ophthalmology, and Genetics, University of Genoa, Genoa, Italy (LD, LB, BA, CF, MDS, CG, LR); Magnetic Resonance Research Centre on Nervous System Diseases, University of Genoa, Genoa, Italy (LB, LS, LC, LR); Neurology Unit, Sant'Andrea Hospital, La Spezia, Italy (MDS); and Department of Neuroradiology, San Martino Hospital, Genoa, Italy (LS, LC). |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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