Document Detail

Whipple's disease presenting with neurological symptoms in an immunosuppressed patient.
MedLine Citation:
PMID:  22675143     Owner:  NLM     Status:  In-Data-Review    
We report an unusual case of Whipple's disease, which remained undiagnosed for several years in a patient being treated with immunosuppressive therapy for many years. The patient presented with a purpuric rash, neurological symptoms, lymphadenopathy and gastrointestinal symptoms. The diagnosis was made by endoscopic biopsy of the duodenum with periodic acid Schiff staining, as well as PCR testing on blood and cerebrospinal fluid. The patient was successfully treated with intravenous ceftriaxone, followed by oral co-trimoxazole for 1 year.
Martijn Weisfelt; Erik Oosterwerff; Mirjam Oosterwerff; Cees Verburgh
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Publication Detail:
Type:  Journal Article     Date:  2012-06-05
Journal Detail:
Title:  BMJ case reports     Volume:  2012     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2012  
Date Detail:
Created Date:  2012-06-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Department of Neurology, Kennemer Gasthuis, Haarlem, Netherlands.
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