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Which nontraditional outcomes should be measured in healthcare decision-making in schizophrenia? A systematic review.
MedLine Citation:
PMID:  23005587     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE:   This article aims to define the utility of nontraditional outcomes (NTOs) in healthcare decision-making in schizophrenia.
DESIGN AND METHODS:   A systematic review of studies published between January 1, 1996, and December 31, 2008, was performed. A 10-point evidence-based utility index (UI) was used to assess the utility of NTOs: high (UI: 7.5-10), medium (UI: ≥5 to <7.5), and low (UI: <5) utility.
FINDINGS:   Of 736 citations identified, 94 met inclusion criteria. One hundred ninety-four NTOs were identified (patient reported outcomes [38.7%] and economic outcomes [61.3%]). Of these, 68 (35.1%) were appropriate for decision making.
PRACTICE IMPLICATIONS:   Numerous NTOs with low utility in schizophrenia are being used for healthcare policy and clinical care by policy makers, managers, and healthcare professionals. Medium and low utility NTOs should be used with caution.
Authors:
Ana Vieta; Xavier Badia; Enric Alvarez; José A Sacristán
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Publication Detail:
Type:  Journal Article     Date:  2012-02-07
Journal Detail:
Title:  Perspectives in psychiatric care     Volume:  48     ISSN:  1744-6163     ISO Abbreviation:  Perspect Psychiatr Care     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401133     Medline TA:  Perspect Psychiatr Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  198-207     Citation Subset:  N    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Affiliation:
Ana Vieta, PharmD, MPhil, is Senior Researcher, Health Economics and Outcomes Research Department, IMS, Barcelona, Spain; Xavier Badia, MD, PhD, is Director, Health Economics and Outcomes Research Department, IMS, Barcelona, Spain; Enric Álvarez, MD, PhD, is Head of the Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Universitat Autónoma de Barcelona, CiberSam, Barcelona, Spain; and José A. Sacristán, MD, PhD, is Director, Clinical Research Department, Lilly S.A., Madrid, Spain.
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