Document Detail

Where are the systematic reviews in transfusion medicine? A study of the transfusion evidence base.
MedLine Citation:
PMID:  20851331     Owner:  NLM     Status:  MEDLINE    
Transfusion medicine has become a large and complex specialty. Although there are now systematic reviews covering many aspects of transfusion, these span a large number of clinical areas and are published across more than a hundred different medical journals, making it difficult for transfusion medicine practitioners and researchers to keep abreast of the current high-level evidence. In response to this problem, NHS Blood and Transplant's Systematic Review Initiative (SRI) has produced a comprehensive overview of systematic reviews in transfusion medicine. A systematic search (to December 2009) and screening procedure were followed by the appraisal of systematic reviews according to predefined inclusion criteria. The 340 eligible systematic reviews were mapped to 10 transfusion intervention groups and 14 topic groups within clinical medicine. Trends in the systematic review literature were examined and gaps in the literature described. The spread of systematic reviews across clinical areas was found to be very uneven, with some areas underreviewed and others with multiple systematic reviews on the same topic, making the identification of the best evidence for current transfusion practice a continuing challenge. References and links to all systematic reviews included in this overview can be freely accessed via the SRI's new online database, the Transfusion Evidence Library (
Carolyn Dorée; Simon Stanworth; Susan J Brunskill; Sally Hopewell; Chris J Hyde; Mike F Murphy
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Transfusion medicine reviews     Volume:  24     ISSN:  1532-9496     ISO Abbreviation:  Transfus Med Rev     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-20     Completed Date:  2011-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8709027     Medline TA:  Transfus Med Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  286-94     Citation Subset:  IM    
Copyright Information:
Crown Copyright © 2010. Published by Elsevier Inc. All rights reserved.
Systematic Review Initiative, NHS Blood and Transplant (Oxford Centre), John Radcliffe Hospital, Oxford, UK.
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MeSH Terms
Blood Transfusion / methods*,  trends
Evidence-Based Medicine* / methods
Models, Biological
Publications / standards,  trends
Regenerative Medicine / methods,  statistics & numerical data
Review Literature as Topic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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