| When oxygen runs short: the microenvironment drives host-pathogen interactions. | |
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MedLine Citation:
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PMID: 22133978 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Pathogens that colonize or infect the human body have to face varying oxygen concentrations within different organs. Inflammation itself promotes oxygen consumption within affected tissues and creates a low oxygen environment. As a consequence, pathogens and the host immune system have to adapt to rapid changes in oxygen availability. Here we summarize recent findings on the adaptation of pathogens, host defense mechanisms and treatment strategies against intracellular pathogens in a low oxygen environment. |
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Authors:
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Inga Dietz; Stefan Jerchel; Marta Szaszak; Kensuke Shima; Jan Rupp |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-20 |
Journal Detail:
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Title: Microbes and infection / Institut Pasteur Volume: - ISSN: 1769-714X ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-12-2 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883508 Medline TA: Microbes Infect Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved. |
Affiliation:
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Institute of Medical Microbiology and Hygiene, University of Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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