Document Detail

When and how should atrial septal defects be closed in adults?
MedLine Citation:
PMID:  19182296     Owner:  NLM     Status:  MEDLINE    
In this review, evidence is presented to indicate that hemodynamically significant (right ventricular volume overload) atrial septal defects (ASDs) in adults should be transcatheter occluded, irrespective of symptomatology. While surgical closure is safe and effective, device closure carries less morbidity. Several devices have been investigated over the last few decades, but at the present time, only two devices, namely, the Amplatzer and the Helex, have received FDA approval; the former is useful in most defects, while the latter is useful in small- and medium-sized defects. A detailed description of Amplatzer device implantation is presented. Finally, approaches to occlude ASDs with complex anatomy are reviewed.
P Syamasundar Rao
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  21     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-02     Completed Date:  2009-06-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  76-82     Citation Subset:  IM    
Division of Pediatric Cardiology, UT-Houston Medical School/Memorial Hermann Children's Hospital, Houston, TX 77030, USA.
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MeSH Terms
Age Factors
Decision Making*
Embolization, Therapeutic / methods*
Heart Septal Defects, Atrial / therapy*
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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