Document Detail

When exercise goes awry: exertional rhabdomyolysis.
MedLine Citation:
PMID:  9160079     Owner:  NLM     Status:  MEDLINE    
Exertional rhabdomyolysis occurs when exercise, often of the eccentric type, damages myofibrils and sarcolemma, with release of the enzyme creatine kinase and pigmented myoglobin into the serum. Severe muscle soreness and dark urine are the hallmark symptoms, and renal failure may develop. Formerly a disease of military recruits, it is now seen more often in exercisers. Although a genetic trait may predispose, the illness probably can be avoided by common sense behavior such as a gradual increase in exercise intensity, proper hydration before, during, and after exercise, and avoiding exercise in extremely hot or humid environments.
R Hamer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  90     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1997 May 
Date Detail:
Created Date:  1997-06-12     Completed Date:  1997-06-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  548-51     Citation Subset:  AIM; IM    
Department of Student Health, University of California, Santa Barbara, USA.
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MeSH Terms
Myoglobinuria / etiology
Rhabdomyolysis / etiology*,  prevention & control,  therapy

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