Document Detail

When is an amniocentesis for fetal maturity unnecessary in nondiabetic pregnancies at risk?
MedLine Citation:
PMID:  6731508     Owner:  NLM     Status:  MEDLINE    
For several years standard obstetric practice has been to perform an amniocentesis for evaluation of fetal maturity. In order to provide a more definitive answer as to which pregnancies need an amniocentesis, a group of 294 nondiabetic pregnant women in whom an amniocentesis for the evaluation of fetal maturity had been performed for clinical indications were evaluated. Three predictors of fetal maturity--obstetric estimate of gestational age, fetal biparietal diameter, and ultrasonic determination of placental maturation--were evaluated for their ability to predict three outcomes of fetal maturity, including positive amniotic fluid phosphatidylglycerol, pediatric estimate of gestational age greater than or equal to 38 weeks, and absence of hyaline membrane disease. A fetal biparietal diameter of greater than or equal to 90 mm was present in 36% of the total population and was associated with 97% term delivery, 87% positive amniotic fluid phosphatidylglycerol, and 0% hyaline membrane disease. The results associated with an obstetric estimate of gestational age of greater than or equal to 38 weeks were similar. In the present data set over one third of clinically indicated amniocenteses could potentially be avoided without losing any predictive capability for fetal maturity.
T L Gross; R J Sokol; G M Kazzi; R N Wolfson; N J Kazzi
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  149     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-07-02     Completed Date:  1984-07-02     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  311-9     Citation Subset:  AIM; IM    
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MeSH Terms
Amniotic Fluid / analysis
Cesarean Section
Fetus / anatomy & histology
Gestational Age*
Hyaline Membrane Disease / epidemiology*
Infant, Newborn
Labor, Obstetric
Phosphatidylglycerols / analysis
Placenta Previa
Pregnancy Complications, Cardiovascular
Prenatal Diagnosis / methods
Grant Support
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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