| When Should F-18 FDG PET/CT Be Used Instead of 68Ga-DOTA-Peptides to Investigate Metastatic Neuroendocrine Tumors? | |
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MedLine Citation:
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PMID: 22064082 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A 67-year-old man, previously operated for a pancreatic neuroendocrine tumor (NET), had progressive increase of serum chromogranin A during follow-up. Sequential Ga-DOTA-NOC and F-18 FDG PET/CT were performed. Ga-DOTA-NOC imaging was negative, whereas F-18 FDG PET/CT showed 2 hypermetabolic hepatic lesions demonstrated at CT-guided biopsy as metastatic deposits from a high-grade (G3) aggressive NET. Despite the large consensus of SPECT or PET with radiolabeled somatostatin analogs as first choice in functional imaging for detecting NETs metastasis, F-18 FDG may occasionally be the right tracer to provide accurate diagnostic and prognostic information in aggressive G3 NET. |
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Authors:
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Chiara Fuccio; Alessandra Musto; Silvia Cambioli; Paolo Castellucci; Maria A Pantaleo; Cristina Nanni; Gian C Montini; Davide Campana; Paolo Tomassetti; Elena Bellan; Arianna Massaro; Gaia Grassetto; Domenico Rubello; Stefano Fanti |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical nuclear medicine Volume: 36 ISSN: 1536-0229 ISO Abbreviation: Clin Nucl Med Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-11-08 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7611109 Medline TA: Clin Nucl Med Country: United States |
Other Details:
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Languages: eng Pagination: 1109-11 Citation Subset: IM |
Affiliation:
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From the *Department of Nuclear Medicine, Azienda Ospedaliero-Universitaria di Bologna, S. Orsola-Malpighi University Hospital, Bologna, Italy; Departments of †Nuclear Medicine, ‡Medical Physics, and §Radiology, S. Maria della Misericordia Hospital, Rovigo, Italy; and Departments of ¶Oncology and ‖Internal Medicine, Azienda Ospedaliero-Universitaria di Bologna, S. Orsola-Malpighi University Hospital, Bologna, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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