| Wheezing illness and re-hospitalization in the first two years of life after neonatal respiratory distress syndrome. | |
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MedLine Citation:
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PMID: 16227035 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To determine the impact of respiratory distress syndrome (RDS) on wheezing illnesses and re-hospitalizations in children as old as 2 years of age. STUDY DESIGN: We observed 2 geographically defined cohorts of children with RDS born after 26 weeks of gestation during 1990 to 1995 and 1996 to 1999 and gestationally paired control subjects. Recurrent wheezing illness and the re-hospitalizations caused by a respiratory condition were recorded. RESULTS: In the first year of life, 47 of 224 infants with RDS and 18 of 224 control subjects born in 1990 to 1995 had recurrent wheezing illness (P <.005) compared with 21 of 109 infants with RDS and 14 of 109 control subjects in the latter cohort (P=.27). A higher number of infants with RDS were readmitted to the hospital (25% versus 13%, P=.002) in the former period, and they spent more days in hospital during both periods. The frequencies of wheezing remained constant in the second year of life, but hospital admissions decreased. Siblings at home, male sex, and bronchopulmonary dysplasia were additional risk factors of wheezing illnesses. CONCLUSION: RDS increases the incidence of wheezing illnesses during the first 2 years of life. Changes in the management of RDS during the 1990s was associated with a decreased incidence of subsequent RDS-associated respiratory morbidity. |
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Authors:
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Maila Koivisto; Riitta Marttila; Timo Saarela; Marja-Leena Pokela; A Marita Valkama; Mikko Hallman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of pediatrics Volume: 147 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-10-17 Completed Date: 2005-12-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: United States |
Other Details:
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Languages: eng Pagination: 486-92 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, Oulu University Hospital, Oulu, Finland. |
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| MeSH Terms | |
Descriptor/Qualifier:
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Case-Control Studies Child, Preschool Female Follow-Up Studies Hospitalization* Humans Infant Infant, Newborn Male Respiration Disorders / etiology* Respiratory Distress Syndrome, Newborn / complications*, therapy Respiratory Sounds / etiology* Risk Factors Treatment Outcome |
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