| Wheel access does not attenuate weight gain in mice fed high-fat or high-CHO diets. | |
| | |
MedLine Citation:
|
PMID: 19927024 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To determine the effect of a high-fat or high-carbohydrate diet and running wheel activity on body composition, body mass, and caloric intake in C57Bl/6 mice. METHODS: At 4 wk of age, five groups of C57Bl/6 mice were housed individually. Two groups had running wheels, whereas the other three groups did not. Within the running wheel groups, FAT-W consumed a high-fat diet (60.3% fat) and CHO-W consumed a high-carbohydrate diet (70.4% carbohydrate). Within the nonrunning groups, FAT consumed the high-fat diet, CHO consumed the high-carbohydrate diet, and the fifth group consumed standard chow. All groups consumed food ad libitum and were exposed to their respective conditions for 12 wk. Wheel activity, food consumption, body mass (BM), and percentage of body fat (%BF) were recorded. RESULTS: There was no significant difference in %BF or BM at the end of 12 wk between FAT-W and FAT or between CHO-W and CHO (P > 0.05). %BF was significantly higher in both FAT-W (42.9% +/- 0.6%) and FAT (45.9% +/- 0.8%) compared with CHO-W (30.8% +/- 1.4%) or CHO (33.4% +/- 1.0%; P < 0.001). BM was significantly higher in both FAT-W (42.8 +/- 0.7 g) and FAT (44.7 +/- 1.2 g) compared with either CHO-W (32.8 +/- 1.6 g) or CHO (37.1 +/- 0.8; P < 0.01). There was no difference in wheel activity between FAT-W and CHO-W (P > 0.05). Daily caloric intake was higher in both FAT-W (17.0 +/- 0.8 kcal) and FAT (15.9 +/- 0.9 kcal) compared with that in CHO-W (13.9 +/- 0.7 kcal) and CHO (13.6 +/- 0.5 kcal; P < 0.01). CONCLUSIONS: Access to a running wheel had no protective effect on BM or %BF in C57Bl/6 mice that consumed either a high-fat or a high-carbohydrate diet during a 12-wk period. Access to a running wheel did not affect caloric intake; however, average daily caloric intake was higher in mice on high-fat diets compared with that in mice on a high-carbohydrate diet. |
| | |
Authors:
|
Alan P Jung; David R Luthin |
Related Documents
:
|
3513534 - Urine c-peptide and creatinine (jaffe method) excretion in healthy young adults on vari... 2453854 - Effects of pvn galanin on macronutrient selection. 16968774 - Evolving resistance to obesity in an insect. 10841934 - Influence of dietary carbohydrate on the metabolism of juvenile litopenaeus stylirostris. 20125104 - Effects of dietary fat modification on skeletal muscle fatty acid handling in the metab... 3821194 - Effects of oltipraz, bha, adt and cabbage on glutathione metabolism, dna damage and lip... |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Medicine and science in sports and exercise Volume: 42 ISSN: 1530-0315 ISO Abbreviation: Med Sci Sports Exerc Publication Date: 2010 Feb |
Date Detail:
|
Created Date: 2010-01-20 Completed Date: 2010-04-29 Revised Date: 2011-07-22 |
Medline Journal Info:
|
Nlm Unique ID: 8005433 Medline TA: Med Sci Sports Exerc Country: United States |
Other Details:
|
Languages: eng Pagination: 355-60 Citation Subset: IM; S |
Affiliation:
|
Samford University, Birmingham, AL 35229, USA. apjung@samford.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Body Composition / physiology Body Mass Index Dietary Carbohydrates / administration & dosage*, metabolism Dietary Fats / administration & dosage*, metabolism Energy Intake Male Mice Mice, Inbred C57BL Obesity / prevention & control* Physical Conditioning, Animal / instrumentation* Random Allocation Weight Gain* |
| Grant Support | |
ID/Acronym/Agency:
|
P30 DK056336-01/DK/NIDDK NIH HHS; P30DK56336/DK/NIDDK NIH HHS; P60 DK079626-01/DK/NIDDK NIH HHS; P60DK079626/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Carbohydrates; 0/Dietary Fats |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evaluation of Multi-Frequency BIA in Assessing Body Composition of Wrestlers.
Next Document: Effects of exercise and L-arginine on ventricular remodeling and oxidative stress.