Document Detail

Wheat threshing dust--a "new allergen" in April-May nasobronchial allergy.
MedLine Citation:
PMID:  8979566     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To identify the allergen(s) responsible for mid April-mid May nasobronchial allergy seen in North India. DESIGN: Case control study. SETTING: Children living in and around Chandigarh (urban, rural). SUBJECTS: 39 children suffering from wheat harvest period (mid April-mid May) respiratory allergy along with randomly selected controls. METHODS: Aerobiological surveys were done from March to June for identification of prevailing allergens for performing allergy tests. Patients were subjected to skin tests (ST), nasal provocation tests (NPT) and bronchial provocation tests (BPT) with extracts prepared from identified pollens and fungal spores. Specific IgE (SIgE) was assayed by ELISA and comparison between pre-season, season and post-season values made. RESULTS: 81% patients had ST positive to antigen of wheat threshing dust (WTD), 30% to fungal antigens, 14% to wheat dust antigens and none to the wheat plant (WP) antigens. Nasal provocation test and bronchial provocation tests were also positive to WTD in 80% and 66% patients, respectively. WTD SIgE was demonstrated in 77% of ST positive patients. CONCLUSIONS: These in vivo and in vitro tests confirm wheat threshing dust as a major causative inhalant allergen for the April-May nasobronchial allergy; in addition, fungal allergens also play a role in 1/3rd of these patients.
S Lavasa; L Kumar; S C Kaushal; N K Ganguli
Related Documents :
20128426 - Food allergy due to olive.
11435726 - Recombinant allergens for skin testing.
22217766 - Multimodal cues drive host-plant assessment in asian citrus psyllid (diaphorina citri).
4008796 - A collaborative study on the first international standard of dermatophagoides pteronyss...
4312276 - Modification of the indirect haemagglutination test for amoebiasis.
3640356 - The d-l test of agreement: a stronger measure of interrater reliability.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Indian pediatrics     Volume:  33     ISSN:  0019-6061     ISO Abbreviation:  Indian Pediatr     Publication Date:  1996 Jul 
Date Detail:
Created Date:  1997-02-05     Completed Date:  1997-02-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  566-70     Citation Subset:  IM    
Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Analysis of Variance
Case-Control Studies
Dust / adverse effects*
India / epidemiology
Respiratory Hypersensitivity / epidemiology*,  immunology,  microbiology
Triticum / adverse effects*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Chemotherapy in Hodgkin's disease.
Next Document:  Community based estimation of perinatal mortality through record linkage.