Document Detail

Wheat grass juice reduces transfusion requirement in patients with thalassemia major: a pilot study.
MedLine Citation:
PMID:  15297687     Owner:  NLM     Status:  MEDLINE    
Wheat grass juice is the juice extracted from the pulp of wheat grass and has been used as a general-purpose health tonic for several years. Several of our patients in the thalassemia unit began consuming wheat grass juice after anecdotal accounts of beneficial effects on transfusion requirements. These encouraging experiences prompted us to evaluate the effect of wheat grass juice on transfusion requirements in patients with transfusion dependent beta thalassemia. Families of patients raised the wheat grass at home in kitchen garden/pots. The patients consumed about 100 mL of wheat grass juice daily. Each patient acted as his own control. Observations recorded during the period of intake of wheat grass juice were compared with one-year period preceding it. Variables recorded were the interval between transfusions, pre-transfusion hemoglobin, amount of blood transfused and the body weight. A beneficial effect of wheat grass juice was defined as decrease in the requirement of packed red cells (measured as grams/Kg body weight/year) by 25% or more. 16 cases were analyzed. Blood transfusion requirement fell by >25% in 8 (50%) patients with a decrease of >40% documented in 3 of these. No perceptible adverse effects were recognized.
R K Marawaha; Deepak Bansal; Siftinder Kaur; Amita Trehan
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Indian pediatrics     Volume:  41     ISSN:  0019-6061     ISO Abbreviation:  Indian Pediatr     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-08-06     Completed Date:  2004-10-19     Revised Date:  2006-09-08    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  716-20     Citation Subset:  IM    
Division of Pediatric Hematology-Oncology, Department of Pediatrics, Advanced Pediatric Center, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India.
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MeSH Terms
Child, Preschool
Erythrocyte Transfusion*
Pilot Projects
Plant Preparations / therapeutic use*
beta-Thalassemia / drug therapy*,  therapy
Reg. No./Substance:
0/Plant Preparations
Comment In:
Indian Pediatr. 2005 Jun;42(6):618-20; author reply 620   [PMID:  15995287 ]
Indian Pediatr. 2006 Jan;43(1):79-80; author reply 80   [PMID:  16465017 ]

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