| What's next after optimal infrapopliteal angioplasty? Clinical and ultrasonographic results of a prospective single-center study. | |
| | |
MedLine Citation:
|
PMID: 18540709 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To evaluate arterial patency and factors influencing outcomes after successful tibial artery angioplasty in patients with critical limb ischemia (CLI). METHODS: From January 2005 to August 2007, a prospective single-center study was conducted involving 80 CLI patients (56 men; mean age 71.7+/-8.8 years) who underwent successful tibial artery angioplasty (<30% residual stenosis) in 87 limbs. Eighty (92%) limbs showed ischemic ulcers or gangrene at baseline. In two thirds, a more proximal lesion was treated, and a secondary stent was implanted in 14 (16%). Follow-up included clinical examination for wound healing (WH), limb salvage (LS), and duplex-documented target vessel patency or restenosis at discharge and at 1, 3, 6, 9, 12, 18, and then every 6 months. Patency rates, WH, and LS were assessed with the Kaplan-Meier method, and factors influencing these outcomes were analyzed using Cox proportional hazards models. RESULTS: Mean follow-up was 10.9 months (range 2 days - 29 months). At 12 months, the primary and assisted primary patency rates were 37.9% and 71.2%, respectively. Restenosis was significantly correlated with smoking (HR 3.58, 95% CI 1.15 to 11.18; p = 0.02), infected ulcers (HR 2.04, 95% CI 1.02 to 4.09; p = 0.04), and posterior tibial artery angioplasty (HR 3.76, 95% CI 1.59 to 8.87; p = 0.003). Rates of LS and WH at 12 months were 92.7% and 74.9%, respectively. Peroneal angioplasty was significantly correlated with WH (HR 1.83, 95% CI 1.04 to 3.25; p = 0.03), and wound healing increased with classes of age (HR 1.60, 95% CI 1.07 to 2.39; p = 0.02). CONCLUSION: One-year restenosis after optimal tibial artery angioplasty is significant and positively correlated with smoking, infection of trophic lesions, and posterior tibial artery angioplasty. Close ultrasound surveillance provides good limb salvage after optimal infrapopliteal angioplasty in patients with CLI. |
| | |
Authors:
|
Mauro Gargiulo; Filippo Maioli; Tanja Ceccacci; Antonio Maria Morselli-Labate; Gianluca Faggioli; Antonio Freyrie; Federica Giovanetti; Gabriele Testi; Natascia Muccini; Andrea Stella |
Related Documents
:
|
2959819 - Surgical treatment of coarctation of the aorta after balloon angioplasty. 11012429 - Peripheral arterial obstruction: prospective study of treatment with a transluminally p... 19019699 - Endovascular management of central thoracic veno-occlusive diseases in hemodialysis pat... 2521479 - Education of patients undergoing coronary angioplasty: factors affecting learning durin... 18789419 - The extent of lower extremity occlusive disease predicts short- and long-term patency f... 23305079 - Segmental dosimetry, toxicity and long-term outcome in patients with prostate cancer tr... 9845139 - Aprotinin counterbalances an increased risk of peri-operative hemorrhage in cabg patien... 7791169 - Protective effect of misoprostol on indomethacin induced renal dysfunction in elderly p... 6688799 - Pirenzepine in long-term therapy for duodenal ulcer. |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists Volume: 15 ISSN: 1526-6028 ISO Abbreviation: J. Endovasc. Ther. Publication Date: 2008 Jun |
Date Detail:
|
Created Date: 2008-06-10 Completed Date: 2008-10-03 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100896915 Medline TA: J Endovasc Ther Country: United States |
Other Details:
|
Languages: eng Pagination: 363-9 Citation Subset: IM |
Affiliation:
|
Department of Vascular Surgery, Alma Mater Studiorum, University of Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy. mauro.gargiulo2@unibo.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Angioplasty, Balloon* / adverse effects Arterial Occlusive Diseases / complications, physiopathology, therapy*, ultrasonography Awards and Prizes Constriction, Pathologic Critical Illness Female Humans Ischemia / etiology, physiopathology, therapy*, ultrasonography Limb Salvage Lower Extremity / blood supply* Male Proportional Hazards Models Prospective Studies Recurrence Risk Assessment Risk Factors Smoking / adverse effects Tibial Arteries / physiopathology, ultrasonography* Time Factors Treatment Outcome Ultrasonography, Doppler, Duplex* Vascular Patency Wound Healing Wound Infection / complications |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Lateral movement of endografts within the aneurysm sac is an indicator of stent-graft instability.
Next Document: Evaluation of wall motion and dynamic geometry of the inferior vena cava using intravascular ultraso...