Document Detail


What's new in cartilage?
MedLine Citation:
PMID:  14518449     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Magnetic resonance (MR) imaging of articular cartilage is important in evaluation of new surgical and pharmacologic treatments for cartilage damage. Many techniques exist for MR imaging of articular cartilage. Standard techniques for morphologic imaging of cartilage include fast spin-echo and spoiled gradient-echo imaging. These methods provide high-resolution morphologic images of cartilage but are time-consuming in the clinical setting. New methods for faster or higher-resolution morphologic imaging include techniques based on steady-state free precession imaging. These fast techniques will allow detailed evaluation of cartilage in the routine clinical setting. There are also several MR imaging methods that may provide information about the structure and physiology of cartilage. Physiologic imaging may allow detailed evaluation of the glycosaminoglycan matrix or collagen network of articular cartilage and may be the most sensitive method for detection of early changes. With the development of new therapies for osteoarthritis and cartilage injury, MR imaging of articular cartilage is of increasing clinical importance. MR imaging will play an important role in evaluation of the effectiveness of these therapies.
Authors:
Garry E Gold; Thomas R McCauley; Martha L Gray; David G Disler
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  23     ISSN:  1527-1323     ISO Abbreviation:  Radiographics     Publication Date:    2003 Sep-Oct
Date Detail:
Created Date:  2003-09-30     Completed Date:  2003-10-27     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1227-42     Citation Subset:  IM    
Copyright Information:
Copyright RSNA, 2003
Affiliation:
Department of Radiology, Stanford University, Packard EE Bldg, Rm 222, Stanford, CA 94305-9510, USA. gold@stanford.edu
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MeSH Terms
Descriptor/Qualifier:
Cartilage Diseases / diagnosis*,  drug therapy,  surgery
Cartilage, Articular / anatomy & histology*,  drug effects,  pathology,  surgery
Humans
Magnetic Resonance Imaging / methods,  trends
Grant Support
ID/Acronym/Agency:
AR41773-04/AR/NIAMS NIH HHS; AR46904-02/AR/NIAMS NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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