Document Detail

What's New in the Treatment of Enterococcal Endocarditis?
MedLine Citation:
PMID:  25165018     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Enterococcus spp. are among the common pathogens causing infective endocarditis (IE). Despite major medical advances and new potent antimicrobial agents, the mortality has not significantly improved for several decades. The usual lack of bactericidal activity of penicillin or ampicillin, the toxicity from the combination of penicillin plus aminoglycosides, and the increased reports of high-level resistance to aminoglycosides have led to the exploration of other regimens for treatment of Enterococcus faecalis IE. As an example, ampicillin plus ceftriaxone is now a well-recognized regimen for this organism. However, the emerging of new drug resistances in Enterococcus faecium dramatically reduces the therapeutic alternatives for this organism in IE which continues to be an immense challenge for clinicians even with the availability of newer antimicrobial agents. This article summarizes the current treatment options for enterococcal endocarditis and reviews of recent publications on the topic.
Masayuki Nigo; Jose M Munita; Cesar A Arias; Barbara E Murray
Related Documents :
11472528 - Polysaccharide production by a reduced pigmentation mutant of aureobasidium pullulans n...
135758 - Regulation of hypoxanthine transport in neurospora crassa.
15611158 - Competing crossover pathways act during meiosis in saccharomyces cerevisiae.
8416898 - Analysis of mrna decay and rrna processing in escherichia coli multiple mutants carryin...
21240698 - Ecological behaviour of three serogroups of legionella pneumophila within a model plumb...
21205398 - Fitness trade-off in peach-potato aphids ( myzus persicae) between insecticide resistan...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current infectious disease reports     Volume:  16     ISSN:  1523-3847     ISO Abbreviation:  Curr Infect Dis Rep     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-08-28     Completed Date:  2014-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888983     Medline TA:  Curr Infect Dis Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  431     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  High-dose daptomycin therapy for staphylococcal endocarditis and when to apply it.
Next Document:  Quadruple wild-type (WT) GIST: defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, ...