Document Detail


Whatever happened to "neonatal hepatitis"?
MedLine Citation:
PMID:  16376793     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
'Idiopathic neonatal hepatitis' is a term that has traditionally been used to denote a clinical syndrome manifest by prolonged jaundice in the neonate. This description is now used much less frequently because recent studies unite well-defined clinical, biochemical and molecular features of intrahepatic cholestasis into specific syndromes. Advances in the understanding of the molecular basis of cholestatic syndromes now enable the classification of syndromes based on biology and offer an opportunity to develop new diagnostic approaches and treatment strategies that take into account the genetic make-up of the child with cholestasis.
Authors:
William F Balistreri; Jorge A Bezerra
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Clinics in liver disease     Volume:  10     ISSN:  1089-3261     ISO Abbreviation:  Clin Liver Dis     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2005-12-26     Completed Date:  2006-05-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9710002     Medline TA:  Clin Liver Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  27-53, v     Citation Subset:  IM    
Affiliation:
Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229-3039, USA. William.Ballestri@cchmc.org
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MeSH Terms
Descriptor/Qualifier:
Bile / metabolism
Cholestasis, Intrahepatic / diagnosis,  genetics*,  therapy
Diagnosis, Differential
Hepatitis / diagnosis,  embryology,  genetics,  therapy
Humans
Infant, Newborn
Infant, Newborn, Diseases / diagnosis,  embryology,  genetics*,  therapy
Metabolism, Inborn Errors / diagnosis,  embryology,  genetics*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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