| What is a normal thyroid-stimulating hormone (TSH) level? Effects of stricter TSH thresholds on pregnancy outcomes after in vitro fertilization. | |
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MedLine Citation:
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PMID: 20655528 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using a thyroid-stimulating hormone (TSH) cutoff of 2.5 mIU/L or 4.5 mIU/L, no differences in the rates of clinical pregnancy, delivery, or miscarriage were observed in this large, retrospective cohort study of first-cycle IVF patients from 2005 through 2008, after controlling for age. Although lowering the TSH threshold to 2.5 mIU/L would result in a nearly fivefold increase in the number of women being classified as hypothyroid, the lack of differences in maternal clinical outcomes must be considered in the current controversy regarding the relative merits of lowering the upper limit of normal of TSH. |
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Authors:
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Andrea Reh; James Grifo; Ann Danoff |
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Publication Detail:
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Type: Journal Article Date: 2010-07-23 |
Journal Detail:
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Title: Fertility and sterility Volume: 94 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-26 Completed Date: 2011-01-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 2920-2 Citation Subset: IM |
Copyright Information:
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Published by Elsevier Inc. |
Affiliation:
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Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, New York University Fertility Center, New York, New York, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Case-Control Studies Cohort Studies Congenital Hypothyroidism / epidemiology Female Fertilization in Vitro* Humans Hypothyroidism / blood*, complications, epidemiology Infertility, Female / blood, complications, therapy Pregnancy / blood* Pregnancy Complications / blood*, epidemiology, etiology Pregnancy Outcome* Reference Values Retrospective Studies Thyrotropin / blood, physiology, standards* |
| Chemical | |
Reg. No./Substance:
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9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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