Document Detail

What factors influence the results of coronary artery bypass grafting in aged patients?
MedLine Citation:
PMID:  17653012     Owner:  NLM     Status:  MEDLINE    
AIM: Early and late results were studied in order to improve the indication for coronary artery bypass grafting (CABG) and to enhance RESULTS: METHODS: A total of 1 973 patients aged 70 years and older who had undergone isolated CABG were studied. Elective operations (EL) were performed in 1 716 patients and 257 patients underwent urgent or emergency operations (UR/EM). Patients were divided into two groups; 104 patients aged 80 years and older (Oct. Group) and 1 869 patients of septuagenarians (Sept. Group). There were no differences between the groups in the number of diseased vessels. RESULTS: Total operative mortality rates in the Oct. and the Sept. groups were 7% and 4%, respectively. The operative mortality of elective surgery was 4% in both groups. The operative mortality of UR/EM CABG was significantly higher in the Oct. group than in the Sept. group (21% vs 6%). Operative mortality was significantly higher in patients with preoperative poor (<49%) left ventricular ejection fraction (LVEF) than in patients with higher (>50%) LVEF (6% vs 3%). Among preoperative risk factors, diabetes mellitus and peripheral vascular disease were significant contributory factors to operative death. In the follow-up study, 70% patients of the Oct. group and 72% patients of the Sept. group survived. Preoperative number of diseased vessels and number of CABG grafts did not influence the early and late RESULTS: CONCLUSION: Preoperative poor LVEF, diabetes mellitus and peripheral vascular disease were significant contributory factors to operative death. When feasible, CABG in octogenarians should be performed electively.
S Ishikawa; B F Buxton; N Manson; A Hadj; S Seevanayagam; J S Raman; G Matalanis; A Rosalion; K Ueda
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  48     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-07-26     Completed Date:  2007-12-19     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  505-8     Citation Subset:  IM    
Department of Cardiac Surgery, Austin Hospital University of Melbourne, Melbourne, Australia.
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MeSH Terms
Age Factors
Aged, 80 and over
Coronary Artery Bypass / adverse effects*,  mortality*
Coronary Artery Disease / complications,  mortality*,  surgery*
Follow-Up Studies
Patient Selection
Retrospective Studies
Risk Factors
Severity of Illness Index
Stroke Volume
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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